Hip And Joint Care Advanced Collagen for Dogs and Cats

Advanced Joint Supplement for senior dogs, cats and pets of all ages experiencing joint stiffness, mobility issues, discomfort, skin conditions, or recovery from strenuous exercise, illness, or surgery. Vet Recommended Joint Supplement with Collagen and Hyaluronic Acid that supports Joint Health in Dogs and cats. Perfect for ageing pets and those of all ages requiring Intensive Joint Care.

Rated 4.88 out of 5 based on 104 customer ratings
(105 customer reviews)

NutriFlex Advanced For Dogs and Cats of all ages and breeds from 8 weeks. Premium nutritional aid in the management of degenerative joint disease.

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Intensive hip and joint care for dogs and cats

5 grams of joint support. 0% nonsense.

NutriFlex® Advanced is a collagen powder for senior dogs and cats and for pets of any age with stiff, sore joints. Every 5 g scoop is 100% active: 3 types of collagen with hyaluronic acid, chondroitin, OptiMSM and vitamin C. Sprinkle it over their meal once a day.

  • Rebuilds cartilage with 1,000 mg of type II collagen that naturally carries chondroitin and hyaluronic acid
  • Cushions and lubricates joints for easier walks, stairs and jumps into the car
  • Strengthens bone, muscle, skin and coat with 3,300 mg of collagen types I and III
  • One tub lasts 50 days for a medium dog and 100 days for a cat or small dog
  • ★★★★★ Loved by SA pet parents
  • Reg. V31175 Act 36/1947
  • Certified human-grade
  • Recommended by veterinarians

Why NutriFlex® Advanced

Every gram in the scoop does a job

Chews and tablets need binders, flavours and carriers to hold their shape. A powder doesn't. So each 5 g scoop of NutriFlex® Advanced is 5,000 mg of joint nutrition, with nothing added to bulk it out, sweeten it or hold it together.

5,000 mgactive ingredients in every 5 g scoop

3collagen types: I, II and III

0fillers, binders, flavours or added sugar

4 gprotein per serving, with 18 amino acids

NutriFlex® Advanced is the intensive formula in the range. It gives your pet everything in NutriFlex® Everyday Maintenance Collagen plus triple-action support for joints, cartilage and bone, for pets that need more than maintenance.

Why collagen

The protein every joint is built from

Collagen is the most abundant protein in your pet's body. Every part of a joint is built on it: the cartilage that cushions it, the bone underneath it and the tendons and ligaments that hold it steady.

Young pets make collagen fast because they're building a whole skeleton. From adulthood, production slows every year. Cartilage thins, joints stiffen and recovery takes longer. That's when you see the slower walks, the pause at the bottom of the stairs and the struggle to get up.

NutriFlex® Advanced is essential daily collagen replenishment for seniors, topping up what their bodies can no longer make enough of on their own.

Type II · Cartilage

Cushions every step

Cartilage is the smooth padding on the ends of the bones that stops them rubbing together. Only type II collagen protein is the main structural component of healthy joint cartilage, responsible for its tensile strength and toughness. NutriFlex® Advanced helps rebuild that cartilage. Our type II collagen also brings natural chondroitin and hyaluronic acid, which cushion and lubricate the joint.

Type I · Bone and tendon

A strong, flexible frame

Type I collagen gives bone the flex to absorb a landing and keeps tendons and ligaments strong enough to hold every joint steady through each jump, sprint and turn.

Type III · Muscle and skin

Supple muscle, healthy coat

Type III collagen keeps muscle, skin and blood vessels strong and elastic, for easier movement, faster recovery and a coat that shines.

Made to reach the joint. Whole collagen is too large to absorb, so NutriFlex® Advanced uses unique low-molecular-weight hydrolysed collagens, broken into tiny peptides your pet's body takes up easily. A 2024 veterinary review reports that collagen hydrolysate is absorbed as amino acids and small peptides that travel to the joint, where it helps protect cartilage, support new collagen and reduce joint inflammation (Blees et al., Journal of Animal Physiology and Animal Nutrition, 2024).

Know the signs

Is your pet feeling it?

Stiff joints rarely announce themselves. Most pets adapt quietly, so the first signs look like a change of habit or just getting older. If any of these sound familiar, their joints are asking for support.

Tick any that sound familiar

  • Slow to get up after a nap or first thing in the morning
  • A pause at the bottom of the stairs
  • No more jumping onto the bed, the couch or into the car
  • Shorter walks and less interest in fetch
  • Stiffness after exercise that takes longer to wear off
  • Cats who swap the windowsill for the floor or stop grooming their lower back

Who feels it sooner

  • Senior dogs and cats, 7 years and up
  • Large and giant breeds, whose joints carry serious weight every day
  • Breeds prone to hip and elbow problems, like Labradors, German Shepherds and Rottweilers
  • Working, sporting and full-time zoomie dogs
  • Pets carrying a few extra kilos
  • Pets recovering from injury or surgery
  • Pets on a mostly processed kibble diet, which offers little of the natural cartilage and connective tissue in fresh food

Cats hide it best. One well-known X-ray study found signs of arthritis in 90% of cats over 12, yet few of them had ever been noticed as stiff or lame (Hardie et al., Journal of the American Veterinary Medical Association, 2002). Cats don't limp and complain. They simply jump less and sleep more. NutriFlex® Advanced is made for cats too: half a level scoop a day, mixed into their meal.

Benefits for dogs and cats

What NutriFlex® Advanced does for your pet

Restores joint cartilage

Type II collagen is the main protein in joint cartilage. NutriFlex® Advanced rebuilds cartilage and blocks the enzymes that break it down.

Why it works: 1,000 mg of type II collagen per scoop, extracted from chicken sternum cartilage with its natural chondroitin and GAGs intact.

Smoother, easier movement

Hyaluronic acid is the main ingredient of the fluid that lubricates every joint. It keeps joints gliding and absorbs the shock of running and jumping.

Why it works: naturally occurring hyaluronic acid comes in the same type II collagen extraction.

Stronger bones and muscle

Collagen gives bone its strength and flexibility. NutriFlex® Advanced supports bone density and helps build and maintain lean muscle.

Why it works: 3,300 mg of hydrolysed collagen types I and III plus 4 g of protein in every scoop.

Glossy coat, healthier skin

Sulphur builds keratin, the protein that makes up skin and coat. Pet parents see the difference in shine as well as in movement.

Why it works: 500 mg of OptiMSM, a concentrated natural source of sulphur, plus collagen for skin elasticity.

Faster recovery

After hard exercise, injury or surgery, NutriFlex® Advanced eases discomfort and gives the body the materials it repairs tissue with.

Why it works: collagen supplies the building blocks and 200 mg of vitamin C drives collagen production.

Fewer free radicals

Free radicals build up during exercise, illness and stress and drive the inflammation that wears joints down.

Why it works: vitamin C neutralises free radicals, topping up what your pet's body makes naturally.

Proof

Don't take our word for it. Take theirs.

★★★★★Loved by pet parents across South Africa

My 13 year old toy poodle was battling with joint pain & since starting Nutriflex about a year ago he has no issues at all.

Darelle McArthur, August 2026

After 1 tin I can see Tyson more willing to go on walks and not lying down the whole day

Stella Bezuidenhout, June 2022

She is back to playing and running (she is 13) and her coat is silky smooth and shining.

Chané D., May 2025

The dog who started it

At 12, we were told it was time to let our very own Mini Schnauzer Hector go. We said no.

We put him on NutriFlex® Advanced every day and he enjoyed another five and a half years, to 17 and a half. He's the reason this tub exists. More years. More love.

The science behind the ingredients

Collagen hydrolysate has been tested in dogs. In a double-blind, placebo-controlled trial of 30 dogs with osteoarthritis, 8 weeks of daily collagen hydrolysate significantly improved vitality and reduced stiffness and lameness (Beynen et al., American Journal of Animal and Veterinary Sciences, 2010).

A 2024 placebo-controlled trial in 31 dogs with osteoarthritis found that bioactive collagen peptides improved gait and quality of life (PLOS ONE, 2024).

These are studies of the ingredient class, not trials of NutriFlex® Advanced itself.

Composition

What's in every 5 g scoop

IngredientPer 5 gWhat it does
Hydrolysed collagen types I and III (bovine)3,300 mgRebuilds bone, tendon, skin and coat
Hydrolysed collagen type II (chicken sternum cartilage)1,000 mgRebuilds joint cartilage. Naturally carries chondroitin, glycosaminoglycans (GAGs), proteoglycans and hyaluronic acid
OptiMSM® (methylsulphonylmethane)500 mgSupplies sulphur for cartilage, connective tissue, skin and coat
Vitamin C (calcium ascorbate)200 mgNeutralises free radicals and drives collagen production
Total5,000 mg100% active ingredients

No fillers, bulking agents, synthetic nutrients, artificial flavours or added sugar (maltodextrin, dextrose). Per serving: 4 g protein, 0 g sugar, 0 g fat, 15 kcal. No shellfish, fish or marine ingredients. Unflavoured.

Compare

The NutriFlex® Hip and Joint Care Advantage

Per level scoop (5 g)NutriFlex® AdvancedOther Brands
Active ingredients100% (5 g)67% (3.3 g)
100% natural ingredientsYesNo
Certified human-grade (suitable for human consumption)YesNo
Undisclosed fillers, binders or artificial flavours0%33% minimum
Added sugar (maltodextrin, dextrose)NoYes
Shellfish or marine derivativesNoYes
Known allergensNoYes
Chondroitin sulphate*YesYes
Glycosaminoglycans (GAGs)*YesYes
MSMYesYes
Vitamin CYesNo
Hyaluronic acid*YesNo
Hydrolysed collagen types I and IIIYesNo
Collagen type II (natural joint care solution)YesNo
Essential amino acidsYesNo
Dietary source of proteinYesNo

*Naturally occurring in the all-in-one type II collagen extraction from chicken sternum cartilage, together with amino acids and antioxidant proteoglycans. All are highly bioavailable for fast absorption.

Directions

How much to give and how long it lasts

Pet weightDaily serving250 g tub lasts
Cats and small dogs, up to 10 kg½ level scoop (2.5 g)100 days
Medium dogs, 11 to 20 kg1 level scoop (5 g)50 days
Large dogs, 21 to 45 kg1½ level scoops (7.5 g)33 days
Giant dogs, 46 kg and over2 level scoops (10 g)25 days

New to NutriFlex®? Double up for the first 4 weeks. Give one serving in the morning and one in the evening, with food. That kick-start uses more powder, so here's how many tubs cover the first month:

  • Cats and small dogs: 1 tub
  • Medium and large dogs: 2 tubs
  • Giant dogs: 3 tubs

How to give it

Sprinkle the powder over your pet's meal, mix it in or dissolve it in a little warm water and pour it over. Give it at least once a day. It's unflavoured, so it disappears into the bowl.

Quality you can verify

Made like your own food

V31175 Act 36/1947

Registered in South Africa

NutriFlex® Advanced is a nutritional supplement for dogs and cats V31175.

Human-grade

Certified human-grade

Made at our own FSA-accredited facility in Cape Town from human-grade ingredients. That's a higher standard than the feed-grade production used for most pet products.

Vet channel

Recommended by veterinarians

Available from veterinary practices and supplied through veterinary wholesale across South Africa.

Questions

Frequently asked questions

How soon will I see a difference?

Give NutriFlex® Advanced at least 8 weeks, which is how long the dogs in the Beynen collagen study were measured over. Some notice it sooner: Stella saw her dog Tyson more willing to go on walks after 1 tub.

Why a powder instead of soft chews or tablets?

Soft chews and tablets need binders, fillers and flavourings to hold their shape and stay soft on the shelf. A powder needs none of them, so every gram of NutriFlex® Advanced is an active ingredient: 5,000 mg of joint nutrition in every 5 g scoop. You can also match the serving exactly to your pet's weight. Cats that refuse tablets eat it without noticing.

Does NutriFlex® Advanced contain fillers or synthetic ingredients?

No. Every scoop is 100% active ingredients: collagen, OptiMSM and vitamin C. There are no fillers, bulking agents, binders, artificial flavours, colourants, preservatives or added sugar such as maltodextrin or dextrose.

Can I give NutriFlex® Advanced with other NutriFlex® supplements?

Yes. Pair it with OmegaMax for omega-3 support for joints, skin and coat, or with DigestiMax for digestion. All 3 go into the same meal.

Should I choose Advanced or Everyday Maintenance Collagen?

Choose Advanced for senior dogs and cats (7 years and older) and for pets of any age that are already stiff, sore or recovering from injury or surgery. Everyday Maintenance Collagen is the daily preventative formula for younger, active pets with healthy joints.

Do cats need joint support too?

Yes, often more than pet parents realise. One well-known X-ray study found signs of arthritis in 90% of cats over 12 (Hardie et al., Journal of the American Veterinary Medical Association, 2002). Cats hide discomfort well, so look for the quiet changes: jumping less, choosing the floor over high spots, sleeping more and grooming less along the back. Half a level scoop of NutriFlex® Advanced a day supports their cartilage, joint fluid and bones.

Is NutriFlex® Advanced suitable for cats?

Yes. Cats get half a level scoop (2.5 g) a day, so one 250 g tub lasts 100 days. NutriFlex® Advanced suits dogs and cats of all ages and breeds from 8 weeks.

Does it contain, taste or smell of shellfish?

No. NutriFlex® Advanced contains no shellfish, fish or marine ingredients. It has no smell. The collagen comes from bovine sources (types I and III) and chicken sternum cartilage (type II), hydrolysed into small peptides.

Can I give my dog human collagen instead?

Human collagen isn't harmful to dogs, but it's the wrong product for them. Human supplements are dosed for human bodies and often contain sweeteners, flavours or preservatives dogs don't need. Many are marine-derived, which dogs with fish allergies react to. NutriFlex® Advanced is dosed by your pet's body weight with nothing added.

Does collagen have side effects?

Collagen is a food protein and dogs and cats tolerate it well. The one effect pet parents occasionally see is mild digestive upset in the first few days, such as loose stools, gas or a change in appetite. It settles as digestion adjusts. If it doesn't, halve the serving for a week and build back up.

More years. More love.

Give them back their good days

One scoop over their meal. Nothing in it but what their joints need.

Add NutriFlex® Advanced to basket

This is a nutritional product and is not intended as a substitute for veterinary products or advice. Discontinue immediately at any sign of adverse reaction. Store at or below 25 °C and protect from moisture.

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4.9
Based on 104 reviews
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Customer photos and videos

Image #1 from Edith Steyn
Image #1 from Natasha
Image #2 from Natasha
Image #3 from Natasha
Image #1 from Anneline Rautenbach
Image #1 from Rosmay
Image #1 from Tanya Le Roux
Image #1 from Stella Bezuidenhout
Image #1 from Kesh Pillay
Image #1 from Edith Steyn

Edith Steyn

Kenzo has a new lease of life with this wonderful powder

Image #1 from Natasha

Natasha

My cat of 19 years are on this to help with her arthirithis, also my 18 year old and a rescue main coon, and they flourish on this product

Image #2 from Natasha

Natasha

My cat of 19 years are on this to help with her arthirithis, also my 18 year old and a rescue main coon, and they flourish on this product

Image #3 from Natasha

Natasha

My cat of 19 years are on this to help with her arthirithis, also my 18 year old and a rescue main coon, and they flourish on this product

Image #1 from Anneline Rautenbach

Anneline Rautenbach

Helpy dog Abby for her joints

Image #1 from Rosmay

Rosmay

Definitely a great product will definitely be ordering some more for my furry baby.

Image #1 from Tanya Le Roux

Tanya Le Roux

Nutriflex Collagen is a great product

Image #1 from Stella Bezuidenhout

Stella Bezuidenhout

After 1 tin I can see Tyson more willing to go on walks and not lying down the whole day

Image #1 from Kesh Pillay

Kesh Pillay

Hi.A brilliant product. I wish I knew about this sooner.This product helped Lola in her last 2 months with me.She started walking again.She passed on at 14yrs on the 5th May 2022.

Image #1 from Edith Steyn
Image #1 from Natasha
Image #2 from Natasha
Image #3 from Natasha
Image #1 from Anneline Rautenbach
Image #1 from Rosmay
Image #1 from Tanya Le Roux
Image #1 from Stella Bezuidenhout
Image #1 from Kesh Pillay
With media
1-20 of 104 reviews
  1. I looks like it really made a difference. We’ll definitely will get some again

  2. The service was very quick and my boy is loving his Nutriflex

  3. Excellent products for energetic dogs especially as they get to their middle to senior years. Better to start them when they are young to achieve the best results.

  4. My 13 year old toy poodle was battling with joint pain & since starting Nutriflex about a year ago he has no issues at all.
    Nutriflex also smells &, I assume!, tastes delicious… my cat & both poodles love it sprinkled over their food ❤️

  5. Helps with my boys shaking legs

  6. Kenzo has a new lease of life with this wonderful powder

    Image #1 from Edith Steyn
  7. Best products I have ever used. Our fur babies deserve the best.

  8. I use both the advanced collagen and digestimax – massive improvement. Can definitely tell the difference when I run out.

  9. I already see a difference in all 3 my dogs’ movement!

  10. My cat of 19 years are on this to help with her arthirithis, also my 18 year old and a rescue main coon, and they flourish on this product

    Image #1 from Natasha
    Image #2 from Natasha
    Image #3 from Natasha
  11. My doggie is thriving since starting her on the Advanced Hip & Joint Care. She is back to playing and running (she is 13) and her coat is silky smooth and shining. She looks like a young child again. It does work wonders!

  12. My big girl does very well on the advanced power. She has more mobility

  13. Excellent product. Will use again.

  14. So far, product seems great

  15. We noticed improvement right away

  16. Works well for our yellow lab

  17. Brilliant product, love it

  18. Great product definitely seen an improvement in my dogs

  19. Have been using this product for over a year and it worked wonders for dog

  20. Verified reviewVerified review - view originalExternal link

    Helpy dog Abby for her joints

    Image #1 from Anneline Rautenbach
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